Fibrosis-4 (FIB-4) Index for Liver Fibrosis. Noninvasive estimate of liver scarring in HCV and HBV patients, to assess need for biopsy.
«We use FIB-4 as an initial assessment. In chronic HCV, when combined with APRI, it has excellent negative predictive value for excluding advanced fibrosis. The positive predictive value is less clear. Those with FIB-4 >1.5 and/or APRI >0.5 often go on to liver elastography.»
